Opera mathematica ou oeuvres mathématicques consists of six chapters, each starts with an individual cover page with decorative illustrations. The main front is assumingely a predecessor of the Hoefler Text with few exceptions in the subtitles, and in the lowest level of subtitle an italic type of the same front is used . The title of each chapter is printed in capital a significantly larger size than that of the subtitles and the texts, followed by the name of the corresponding author in italic capital, then followed by the subtitles in italic. The text itself is organized in two columns separated by two fine lines, surrounded by a broad margin that takes up approximately 1/8 of the length of the page.
A large amount of illustrations are employed to depict the theories and methods described in the text, including architectural drawings, perspective views and constructions of geometry. Most of the depictions are schematics drawn with guides and grids, showing the detailed plotting methods of the relevant content. They are always concentrated after the text part of each chapter, each illustration taking up one full page. Every object shown in the illustrations is numbered and the number is then referenced in the text before; however, the illustrations themselves are originally not numbered. The numbering was later completed by Atelier Strebel AG during a restoration in 2011, when each illustration was labeled with hand-written numbers with pencil.
The illustrations are distributed in 265 pages, while the entire work counts 750 pages. Since the back page of each illustration is spared of content, only less than 220 pages are filled with text, suggesting the importance of the illustrations to this schematic-orientated work.
The work explains the methods of construction in several areas with both texts and depictions referencing each other and can be therefore categorized in the genre of the handbook.